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Tadalista 10 mg is a prescription medication used to treat erectile dysfunction (ED) in men. It contains 10 mg of tadalafil, a long-acting PDE5 inhibitor that improves blood flow to the penis, helping to achieve and sustain a firm erection during sexual stimulation. Tadalafil works by inhibiting the phosphodiesterase type 5 (PDE5) enzyme, which breaks down cGMP, a chemical that promotes the relaxation of smooth muscle in the penis. When PDE5 is blocked, cGMP levels increase, leading to better blood flow and a more reliable erection during sexual activity.