Fildena 150 mg is a high-dose medication containing sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor. It works by enhancing blood flow to the penile area during sexual stimulation, enabling stronger and longer-lasting erections. However, its effectiveness and side effects can vary based on body weight, composition, and individual health factors. Individuals with higher body weights may experience diluted drug concentrations due to larger blood volumes. This might slightly delay the onset of action but does not typically reduce efficacy if taken as prescribed. People with lower body weights may experience higher relative drug concentrations, potentially leading to faster effects or an increased likelihood of side effects like headache, flushing, or dizziness. Fildena 150 mg is water-soluble, not fat-soluble, so fat composition has minimal direct effect. However, excess fat may contribute to reduced cardiovascular health, which could influence the drug's effectiveness in improving blood flow. In leaner individuals, the drug may act more predictably due to potentially better cardiovascular health and circulation.