Cenforce 130 mg can differ between individuals because of several factors related to the person, the dose, and how the body processes the drug. Even though the active ingredient — sildenafil citrate — is the same in all Cenforce tablets, the 130 mg dose is higher than typical starting doses, which increases the likelihood and intensity of side effects. Here’s why side effects may Dose‑related effects Higher doses like 130 mg produce stronger effects on blood vessels and the cardiovascular system, which can increase the risk of headache, flushing, dizziness, or low blood pressure. People on lower doses (like 50 mg or 100 mg) may Cenforce 130 mg  fewer or milder side effects.   Individual metabolism Each person metabolizes sildenafil differently. Liver function, age, and genetics can affect how quickly the drug is broken down, which influences both effectiveness and side effects. Slower metabolism → higher drug levels in the blood → more pronounced side effects.   Other health conditions Heart disease, high or low blood pressure, kidney or liver issues can increase sensitivity to sildenafil, making some side effects more likely or severe Other medications Drugs like nitrates, alpha‑blockers, or certain antifungals/antibiotics can interact with sildenafil, changing how it works in your body and sometimes intensifying side effects. Lifestyle factors Alcohol, heavy meals, or recreational drugs can also alter the drug’s absorption or effects, affecting side effect intensity. The higher the dose (like 130 mg), the more likely and stronger the side effects can be. That’s why doctors usually start with 50 mg or 100 mg and only increase if needed, under supervision.