Yes, several conditions can make Fildena Super Active (a medication commonly used for erectile dysfunction, containing sildenafil) ineffective or less effective. First, underlying health issues like severe cardiovascular disease, uncontrolled diabetes, or neurological disorders can impair blood flow or nerve function, reducing the drug’s effectiveness.

Second, taking certain medications such as nitrates or alpha-blockers can interfere with how Fildena works. Third, psychological factors like severe stress, anxiety, or depression may reduce its effectiveness by affecting sexual arousal. Additionally, lifestyle factors such as excessive alcohol consumption or smoking can also blunt its effects. Finally, improper usage, such as taking it without sexual stimulation or incorrect timing, may result in poor efficacy.