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Tazzle 20 mg is an effective treatment for ED, offering a higher dose for men who have not responded to lower doses. As with any medication, it's essential to follow your healthcare provider's instructions and be aware of potential side effects and interactions. Always consult with a healthcare provider before starting any new medication. Tadalafil, the active ingredient in Tazzle 20 mg, works by inhibiting the PDE5 enzyme, leading to increased levels of cyclic GMP (cGMP). This results in the relaxation of smooth muscles and dilation of blood vessels in the penis, thereby improving blood flow and enabling an erection when sexually stimulated.