Malegra DXT Plus from your system depends on the half-lives of its two active ingredients: Sildenafil Citrate and Duloxetine. Hotmedz +9 myedstore.com +9 polydynamic.com.my Half-Life and Elimination Sildenafil Citrate: The half-life is approximately 3 to 5 hours, meaning it takes about 3 to 5 hours for half of the drug to be eliminated from the body. Complete elimination typically occurs within 18 to 24 hours after ingestion. Duloxetine: This medication has a half-life of approximately 12 hours, so it takes about 12 hours for half of the drug to be eliminated. Full clearance may take 2 to 3 days. Total Time for Elimination Malegra DXT Plus both components, Malegra DXT Plus is likely to be cleared from your system within 1 to 3 days. However, individual factors such as metabolism, age, liver function, and overall health can influence this timeframe. Important Considerations Alcohol and Food: Consuming alcohol or high-fat meals can affect the absorption and metabolism of these medications, potentially altering their elimination rates. Liver Function: Both Sildenafil and Duloxetine are metabolized in the liver. Impaired liver function can slow down their elimination. polydynamic.com.my +1 MedicinesFAQ +1 Kidney Function: Since both drugs are excreted through the kidneys, any renal impairment may prolong their presence in the body. Drug Interactions: Concurrent use of other medications can affect the metabolism and elimination of Malegra DXT Plus.  Summary Under typical conditions, Malegra DXT Plus should be eliminated from your system within 1 to 3 days. If you have concerns about how this medication may interact with other substances or affect your health, it's advisable to consult a healthcare professional.