​Cenforce D is a combination medication containing Sildenafil Citrate and Dapoxetine, designed to treat both erectile dysfunction (ED) and premature ejaculation (PE) in men. While specific clinical studies on Cenforce D itself are limited, extensive research has been conducted on the individual components and their combined use.​ Sildenafil Citrate: Sildenafil is a well-established treatment for ED. Clinical studies have demonstrated that for men with ED of various etiologies, sildenafil significantly improves the ability to achieve and maintain erections. It is rapidly absorbed, with peak plasma concentrations reached within about an hour, and has a terminal half-life of 3–5 hours, supporting its use as an ​Cenforce D treatment. ​ PubMed Central Dapoxetine: Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) approved for the treatment of PE. Clinical trials have shown that dapoxetine is effective and generally well-tolerated, with common side effects including nausea, dizziness, and headache. Unlike other SSRIs, dapoxetine is associated with low rates of sexual dysfunction. ​ ecronicon.net   Wikipedia  Combination Therapy: Research into the combined use of sildenafil and dapoxetine indicates enhanced efficacy in treating men with both ED and PE. A randomized, placebo-controlled clinical trial compared the on-demand use of paroxetine, dapoxetine, sildenafil, and a combination of dapoxetine with sildenafil in patients with PE. 

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