Avana 200 mg contains Avanafil, a PDE5 inhibitor used to treat erectile dysfunction (ED). While Avanafil can be effective for ED, it may interact with other medications, particularly those used for high blood pressure (hypertension). Key Considerations for High Blood Pressure: PDE5 inhibitors, including Avanafil, work by dilating blood vessels, which lowers blood pressure. In most cases, this can be beneficial for men with both ED and high blood pressure. However, this effect can be dangerous if combined with certain antihypertensive medications (especially nitrates), leading to severe hypotension (dangerously low blood pressure). The 200 mg dosage is considered a high dose, and it is not typically recommended for routine use, especially in men with high blood pressure. Lower doses are usually preferred for better safety and effectiveness. Avoiding Avana 200 mg Dosage for High Blood Pressure: Nitrates (e.g., Nitroglycerin): Avoid using Avana 200 mg if you are taking any form of nitrate medications (commonly prescribed for chest pain or angina). Combining nitrates with Avanafil can cause a severe drop in blood pressure that can be life-threatening. Alpha-Blockers: If you are taking alpha-blockers (common for high blood pressure or prostate issues), combining them with Avana 200 mg can cause low blood pressure and dizziness. A lower dose of Avanafil (such as 50 mg or 100 mg) is recommended in such cases. Other Antihypertensive Medications: If you're on calcium channel blockers or ACE inhibitors, these medications can also lower blood pressure, and using Avana 200 mg could intensify this effect, leading to dizziness or fainting. Recommended Dosage for High Blood Pressure: For men with high blood pressure, lower doses of Avanafil are often recommended to avoid severe hypotension. The typical starting dose for Avanafil is 50 mg, and this can be adjusted to 100 mg depending on individual tolerance. 200 mg is considered a higher dose and should be avoided unless specifically directed by a healthcare provider, especially for those on blood pressure-lowering medications. General Safety Tips: Consult Your Doctor: Always consult your healthcare provider before using Avanafil or any ED medication, especially if you have a history of high blood pressure or are taking medications for it. Avoid Overuse: Higher doses like 200 mg should not be used as a routine dosage, especially in combination with antihypertensive drugs, to prevent dangerous drops in blood pressure. Monitor Blood Pressure: If you are prescribed Avanafil, ensure your blood pressure is monitored regularly by your healthcare provider.