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MarkNtel Advisors has released a new report that highlights the strong growth trajectory of the Organ-on-Chip Market, The Global Organ-on-Chip Market size was valued at around USD 126 million in 2024 and is projected to reach USD 950 million by 2030. Along with this, the market is estimated to grow at a CAGR of around 40% during the forecast period (2025-30). Various factors are attributed to the growth of the market like growth in automobile production, growing focus on lightweight & sustainable materials, rising demand for luxury & customized interiors, increasing focus on safety standards, and the adoption of Advanced Driver Assistance Systems (ADAS). The report provides valuable insights into the drivers, trends, and challenges shaping the future of the Organ-on-Chip Market. It offers an in-depth look at the key players, geographical performance, and the segments leading the charge in market share.
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The Organ-on-Chip Market explores the industry by emphasizing the growth parameters and categorizes including geographical segmentation, to offer a comprehensive understanding of the market dynamic. The further bifurcations are as follows:
Based on organ type, the Liver segment leads the global market. It holds approx. 30% of the total market value. Their extensive use in liver disease studies, toxicity testing, and drug metabolism contributes to the high percentage share.
Based on end users, pharmaceutical and biotechnology lead the market. It holds approx. 73% market share. This growth is because of their considerable use of OoC systems for drug discovery, testing of toxicity, and the modeling of diseases.
Out of them, North America dominates the Global Organ-on-Chip Market. It holds approx. 52% market share. The region is supported by robust investments in biomedical research, superior infrastructure, and the presence of major industry players.
Growing Demand for Alternatives to Animal Testing in Drug Discovery – The worldwide market for organ-on-chip technology is driven by the growing need for alternatives to animal testing in drug discovery. To enhance safety & efficacy evaluations and lessen the ethical issues surrounding animal testing regulatory organizations like the FDA and EMA promote the use of sophisticated in-vitro models. The FDA Modernization Act 2.0. passed by the USA government in the year 2022, will greatly decrease the use of animal drug testing by promoting the use of substitute techniques like organ-on-chips. Precise simulation of human organ function through systems such as the liver and lung on chips offers increased predictive accuracy of drug toxicity and metabolism studies. For instance; Emulate's liver on a chip has been widely utilized to predict hepatotoxicity in candidates for drugs reducing dependence on animal models. This shows how Organ-On-Chip technology is changing the scenario of preclinical testing to provide ethical and cost-effective solutions for the pharmaceutical industry with alternatives to animal testing.
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Development of Multi-Organ-on-Chip Systems – The development of multi-organ-on-chip systems provides a big opportunity in the organ-on-chip industry. These complex models can better mimic complicated interactions between different organs by allowing more realistic simulations of human physiology. For instance, the laboratories of TissUse GmbH are already working with 2- and 4-organ chips. These systems are of particular value in the study of drug metabolism and organ toxicity across multiple systems simultaneously, which is important for the assessment of the effects of new therapies and understanding diseases like cancer and metabolic disorders. As the demand for accurate, personalized medicine increases, the multi-organ-on-chip platforms can augment drug discovery, toxicity testing, and the development of personalized treatment. This innovation is likely to bring about huge market expansion as pharmaceutical and biotech companies move toward finding more advanced testing solutions.
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