There are a lot of Loot Filters available for Path of Exile 2, which highlight valuable or useful item drops and hide items that you can't use or aren't worth picking up. Loot Filters are practically required in high-tier Waystone maps where enemy drops will cover virtually your entire screen if not filtered.
Once you reach the endgame for PoE 2, you should also consider installing the Sidekick addon. This third-party program runs in the background, separate from the game, and enables several enhancements to the user experience, including map and price-checking capabilities, a way to Path of exile currency search for items throughout all of your stashes, and much more.
Pick Up & Salvage All Socketed & Quality Gear
Though you don't need to POE currency for sale pick up everything that drops in Path of Exile 2, gear with Rune Sockets or Quality is extremely valuable. When you Salvage these items you will get Armorer's Scrap, Blacksmith's Whetstone, and Shards that build up to an Artificer's Orb - an item that adds a Rune Socket to any piece of gear.